The book describes a computational model of the immune system reaction, C-ImmSim, built along the lines of the computer model known as the Celada-Seiden model (CS-model). The computational counterpart of the CS-model is called IMMSIM which stands for IMMune system SIMulator. IMMSIM was written in 1992 by the physicist Phil E. Seiden and the immunologist Franco Celada. This model was built around the idea of developing a computerized system to perform experiments similar in vivo experiments; a tool developed to help biologists testing theories and hypothesis about how the immune system works.
C-ImmSim is best viewed as a collection of models in a single program. It incorporates the principal core facts of today’s immunological knowledge, such as the diversity of specific elements, MHC restriction, clonal selection, thymic education of T cells, antigen processing and presentation (both the cytosolic and endocytic pathways are implemented), cell-cell cooperation, homeostasis of cells created by the bone marrow, hyper mutation of antibodies, maturation of the cellular and humoral response, and memory. Besides, an antigen can represent a bacterium, a virus, or an allergen or a tumor cell. C-ImmSim has been recently customized to simulate the HIV-1 infection. Moreover, it can simulate the immunotherapy for cancer. These features are all present in the code and people can choose to turn them on and off at compiling time.
The book presents the basic model as well as the various customizations to implement the description of different diseases and the way they have been used in practice to produce new knowledge either from hypothesis or from lab-experiment data. In this respect, the book can be used as a practical guide to implement a computational model with which to study a specific disease and to try to address realistic clinical questions.Immune System Model A&P II Kwan Christenson. Our Amazing Immune System A puppet show of the basic functions of our immune system. Written and performed by Tory Brady of the Exploratorium Teacher ... Our Immune System - Pfizer - Cortical Studios / Glow Studio "Our Immune System," is an award-winning movie commissioned by Pfizer BV, that shows the complexity of inflammation and ... Immune System Explore the basics about the immune system with The Amoeba Sisters! This video talks about the three lines of defense and also ... How does your immune system work? - Emma Bryce Explore how your immune system's vast network of cells, tissues, and organs coordinate your body's defenses against bacteria, ... IMMUNE SYSTEM MADE EASY- IMMUNOLOGY INNATE AND ADAPTIVE IMMUNITY SIMPLE ANIMATION The immune system is the basic defence system of the body that protects us from harmful pathogens and diseases. GERM ... Systems Modelling Take the full course: Follow along with the eBook: Twitter: ... Immune System: Innate and Adaptive Immunity Explained The immune system (or immunity) can be divided into two types - innate and adaptive immunity. This video has an immune system ... Immune System, Part 1: Crash Course A&P #45 Our final episodes of Anatomy & Physiology explore the way your body keeps all that complex, intricate stuff alive and healthy ... Immune System Modelling and Why it is Important | COVID-19 | Breakthrough Junior Challange 2020 This year, we don't expect that pandemic will exist again. And we are so confused about living because the vaccine of this new ... Modelling the Immune Response Whether you're developing immunotherapies or agents targeting autoimmune disease, you'll need to effectively model the ... HOW IMMUNE SYSTEM WORKS 3D ANIMATION Explain immune system in easy way the video is translated into different language activate captions(CC) in the video for ... The Immune System Explained I – Bacteria Infection Every second of your life you are under attack. Bacteria, viruses, spores and more living stuff wants to enter your body and use its ... The Top 10 Ways To Fortify Your Immune System Visit to subscribe for free updates, new episodes and much more. On this episode you will learn: ... Oxford Mathematician explains SIR Disease Model for COVID-19 (Coronavirus) The SIR model is one of the simplest disease models we have to explain the spread of a virus through a population. I first explain ... IMMUNE RESPONSE For more information: [email protected] ... The Immune System: Overview In this video, Dr Matt explains: - The two divisions of the immune system - How these divisions work to provide your body with ... Understanding the Cells of the Immune System A visual explanation of the cells of the immune system and their different functions that provide an immune response to an ... The MATH of Epidemics | Intro to the SIR Model How do organizations like the WHO and CDC do mathematical modelling to predict the growth of an epidemic? In this video we ... Immune System | Summary has diagrams, notes, and practice questions. Quizlet Review: The ...
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